| name | Hub | image | date Ceased operations | date Commenced operations | IATA Code | ICAO Code | city Headquarters | administrative division Headquarters | country Headquarters | continent Headquarters | Country | continent | Parent | number of aircrafts | number of destinations | Website |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Air Djibouti | Djibouti–Ambouli International Airport |  | 2002 | 1963 | DY | DJU | Djibouti (city) | Djibouti | Djibouti | Africa | Djibouti | Africa | Website | |||
| Djibouti Air | Djibouti–Ambouli International Airport | 2011 | DA | Djibouti (city) | Djibouti | Djibouti | Africa | 1 | 2 | Website | ||||||
| Djibouti Airlines | Djibouti–Ambouli International Airport | 2009 | 1996 | D8 | DJB | Djibouti (city) | Djibouti | Djibouti | Africa | Djibouti | Africa | 5 | 8 | Website | ||
| Puntavia Airline de Djibouti | 1996 | 1991 | PTV | Djibouti (city) | Djibouti | Djibouti | Africa | Website | ||||||||
| Silver Air (Djibouti) | 2009 | 2004 | SVJ | Djibouti (city) | Djibouti | Djibouti | Africa | United States | Americas | Website |