| name | Hub | image | date Ceased operations | date Commenced operations | IATA Code | ICAO Code | city Headquarters | administrative division Headquarters | country Headquarters | continent Headquarters | Country | continent | Parent | number of aircrafts | number of destinations | Website |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FedEx Express | Memphis International Airport |  | 17/04/1973 | FX | FDX | Memphis, Tennessee | Tennessee | United States | Americas | United States | Americas | 659 | 375 | Website | ||
| Mesaba Airlines | Detroit Metropolitan Airport |  | After 04/01/2012 | 04/02/1974 | XJ | MES | Memphis, Tennessee | Tennessee | United States | Americas | United States | Americas | Pinnacle Airlines Corp. | 86 | 64 | Website |
| RegionsAir | St. Louis Lambert International Airport | 25/05/2007 | 16/12/1996 | 3C | CEA | Smyrna, Tennessee | Tennessee | United States | Americas | United States | Americas | RegionsAir | Website | |||
| Southern Airways Express | Memphis International Airport | 2013 | 9X | LTD | Memphis, Tennessee | Tennessee | United States | Americas | United States | Americas | 23 | 10 | Website | |||
| Contour Aviation | 1982 | LF | VTE | Smyrna, Tennessee | Tennessee | United States | Americas | United States | Americas | 27 | Website |