| name | Hub | image | date Ceased operations | date Commenced operations | IATA Code | ICAO Code | city Headquarters | administrative division Headquarters | country Headquarters | continent Headquarters | Country | continent | Parent | number of aircrafts | number of destinations | Website |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Africa World Airlines | Kotoka International Airport |  | 21/09/2012 | AW | AFW | Accra | Greater Accra Region | Ghana | Africa | Ghana | Africa | Hainan Airlines | 5 | 4 | Website | |
| Antrak Air | Kotoka International Airport |  | 09/2003 | O4 | ABV | Accra | Greater Accra Region | Ghana | Africa | Ghana | Africa | 5 | Website | |||
| Ghana Airways | Kotoka International Airport |  | 2005 | 15/07/1958 | GH | Accra | Greater Accra Region | Ghana | Africa | Ghana | Africa | Government of Ghana | Website | |||
| Ghana International Airlines | Kotoka International Airport |  | 13/05/2010 | 2005 | G0 | GHB | Accra | Greater Accra Region | Ghana | Africa | Ghana | Africa | 1 | 4 | Website | |
| Eagle Atlantic Airlines | Kotoka International Airport | 2014 | 10/2013 | E2 | EAB | Accra | Greater Accra Region | Ghana | Africa | Ghana | Africa | 1 | 5 | Website |