| name | Hub | image | date Ceased operations | date Commenced operations | IATA Code | ICAO Code | city Headquarters | administrative division Headquarters | country Headquarters | continent Headquarters | Country | continent | Parent | number of aircrafts | number of destinations | Website |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Air Sunshine | Luis Muñoz Marín International Airport |  | 1982 | YI | RSI | Fort Lauderdale, Florida | Florida | United States | Americas | United States | Americas | 3 | 10 | Website | ||
| Four Star Air Cargo | Luis Muñoz Marín International Airport | 2009 | 1982 | HK | FSC | United States | Americas | 6 | Website | |||||||
| Seaborne Airlines | Luis Muñoz Marín International Airport | 1992 | BB | SBS | San Juan, Puerto Rico | Puerto Rico | United States | Americas | United States | Americas | 10 | 15 | Website | |||
| Borinquen Air | Luis Muñoz Marín International Airport | 1961 | BNA | San Juan, Puerto Rico | Puerto Rico | United States | Americas | United States | Americas | 2 | Website |