| name | Hub | image | date Ceased operations | date Commenced operations | IATA Code | ICAO Code | city Headquarters | administrative division Headquarters | country Headquarters | continent Headquarters | Country | continent | Parent | number of aircrafts | number of destinations | Website |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aerolíneas Paraguayas | Silvio Pettirossi International Airport | 2002 | 1994 | A8 | PAY | Luque | Central Department | Paraguay | Americas | Paraguay | Americas | LATAM Brasil | Website | |||
| Air guarani | 2011 | Asunción | Asunción | Paraguay | Americas | Paraguay | Americas | 1 | 16 | Website | ||||||
| Líneas Aéreas Paraguayas |  | 1994 | 1963 | PZ | LAP | Asunción | Asunción | Paraguay | Americas | Paraguay | Americas | 19 | 23 | Website | ||
| Regional Paraguaya | Silvio Pettirossi International Airport |  | 2009 | 2008 | P7 | REP | Asunción | Asunción | Paraguay | Americas | Paraguay | Americas | 2 | 4 | Website | |
| Sol del Paraguay | Guaraní International Airport |  | 01/08/2012 | 15/07/2011 | PI | SGU | Asunción | Asunción | Paraguay | Americas | Paraguay | Americas | 3 | 3 | Website |