| name | Hub | image | date Ceased operations | date Commenced operations | IATA Code | ICAO Code | city Headquarters | administrative division Headquarters | country Headquarters | continent Headquarters | Country | continent | Parent | number of aircrafts | number of destinations | Website |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1time Airline | O. R. Tambo International Airport |  | 02/11/2012 | 25/02/2004 | 1T | RNX | Johannesburg | Gauteng | South Africa | Africa | South Africa | Africa | 1time Airline | 11 | 9 | Website |
| Kulula.com | O. R. Tambo International Airport |  | 2001 | MN | CAW | Bonaero Park | Gauteng | South Africa | Africa | South Africa | Africa | Comair | 10 | 6 | Website | |
| Mango (airline) | O. R. Tambo International Airport |  | 2006 | JE | MNO | Johannesburg | Gauteng | South Africa | Africa | South Africa | Africa | South African Airways | 10 | 6 | Website | |
| Mistral Aviation | 2009 | 2006 | Johannesburg | Gauteng | South Africa | Africa | South Africa | Africa | 2 | Website | ||||||
| Nationwide Airlines (South Africa) | O. R. Tambo International Airport |  | 2008 | 1995 | CE | NTW | Johannesburg | Gauteng | South Africa | Africa | South Africa | Africa | 17 | 8 | Website |