| name | Hub | image | date Ceased operations | date Commenced operations | IATA Code | ICAO Code | city Headquarters | administrative division Headquarters | country Headquarters | continent Headquarters | Country | continent | Parent | number of aircrafts | number of destinations | Website |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pakistan International Airlines | Jinnah International Airport |  | 1946 | PK | PIA | Karachi | Sindh | Pakistan | Asia | Pakistan | Asia | 2(x)ist | 38 | 82 | Website | |
| Pearl Air | Jinnah International Airport | 2004 | PRL | Karachi | Sindh | Pakistan | Asia | Pakistan | Asia | 6 | Website | |||||
| Shaheen Air |  | 25/10/1994 | NL | SAI | Karachi | Sindh | Pakistan | Asia | Pakistan | Asia | 23 | Website | ||||
| Star Air Aviation | Jinnah International Airport | 2000 | 6S | URJ | Karachi | Sindh | Pakistan | Asia | Pakistan | Asia | 3 | 7 | Website | |||
| Vision air international | Jinnah International Airport |  | 2006 | VIS | Karachi | Sindh | Pakistan | Asia | Pakistan | Asia | 4 | Website |